Fucidin is a widely used brand name for fusidic acid, a topical antibiotic formulated as a cream or ointment. It targets gram-positive bacteria—especially Staphylococcus aureus—by inhibiting bacterial protein synthesis. Clinicians commonly prescribe Fucidin to treat superficial skin infections such as impetigo, infected eczema (dermatitis), folliculitis, and minor wound infections. In many countries, Fucidin is available as a 2% fusidic acid preparation. Because resistance can increase with prolonged or inappropriate use, therapy is usually short and focused. Note that fusidic acid topical products are not currently FDA-approved in the United States, and availability varies by region and brand name.
Fucidin (fusidic acid) is indicated for bacterial skin infections where susceptible organisms are implicated. The most common uses include impetigo, infected atopic dermatitis, folliculitis and furuncles (boils) with minor drainage, small traumatic wound infections, and minor surgical site infections when limited in size and depth. It is frequently chosen when staphylococcal involvement is suspected, including cases of impetigo or localized crusting skin lesions in children and adults. In some regions, fusidic acid retains reliable activity against methicillin-sensitive Staphylococcus aureus (MSSA) and, variably, certain strains of MRSA; however, susceptibility patterns differ by community, so local guidance is important.
Clinicians may also use Fucidin to treat secondarily infected skin conditions such as eczema or psoriasis when bacterial superinfection occurs. It is not intended for nonbacterial infections: do not use for viral lesions (e.g., cold sores, shingles, chickenpox), fungal infections (e.g., ringworm, athlete’s foot), or parasitic infestations (e.g., scabies) unless a clinician co-prescribes appropriate agents for those causes. It is also not a substitute for systemic antibiotics when deeper, spreading, or systemic infections are present, such as cellulitis with fever, abscesses requiring incision and drainage, or when symptoms rapidly worsen.
Typical dosing for Fucidin cream or ointment (2% fusidic acid) involves applying a thin layer to the affected area two to three times daily for 5–7 days, or up to 10 days as directed. In many clinical settings, twice-daily application is sufficient for localized infections; more frequent application rarely improves outcomes and may increase irritation. Before applying, wash hands, gently cleanse the infected skin with mild soap and water or saline, pat dry, then apply a small amount just enough to cover the lesion. Avoid thick layers; a pea-sized amount often treats an area about the size of a two-inch circle. Wash hands again after application unless treating the hands.
If a clinician recommends a dressing, apply Fucidin first, allow it to absorb briefly, then cover with a sterile, non-occlusive dressing. Occlusive dressings can increase absorption and are generally avoided unless specifically advised. For crusted impetigo, gently softening and removing crusts with warm water before applying may help the antibiotic reach the affected skin. Keep Fucidin away from the eyes, inside the nose, and mucous membranes; if contact occurs, rinse thoroughly with water. Do not use concurrently with other topical products on the same site unless directed, as layering can dilute or inactivate the antibiotic and increase irritation. Complete the full course even if the area looks better sooner, and arrange follow-up if there is no improvement within 2–3 days or if symptoms worsen.
Use Fucidin exactly as prescribed to minimize the risk of bacterial resistance. Limit treatment to the smallest area necessary and the shortest effective duration—typically less than 10 days. Avoid using Fucidin repeatedly on the same site without medical review; recurring infections may reflect resistant organisms, incorrect diagnosis (e.g., eczema herpeticum, tinea), or an underlying skin barrier issue that requires a different approach. Do not use on large body surface areas, under occlusive dressings, or on broken skin that is extensive unless a clinician supervises the plan. If the infection appears to spread rapidly, is accompanied by fever, severe pain, or red streaking, seek urgent medical care for possible systemic treatment.
Allergy is uncommon but possible. Stop use and consult a clinician if you experience signs of hypersensitivity, such as severe itching, hives, swelling, or blistering at the application site. Some formulations may contain ingredients like lanolin, cetyl alcohol, or parabens that can trigger contact dermatitis in sensitive individuals. Those with chronic skin conditions (e.g., atopic dermatitis) should use skin-friendly cleansers and moisturizers alongside Fucidin to restore the skin barrier and help prevent reinfection. Avoid combining Fucidin with topical corticosteroids unless specifically instructed—though combination products exist in some markets, inappropriate steroid use can mask infection, delay healing, and increase risk of side effects.
Fucidin is contraindicated in anyone with a known hypersensitivity to fusidic acid or any component of the formulation. It should not be used for nonbacterial infections, including viral (e.g., herpes simplex, varicella-zoster) or fungal (e.g., dermatophytes, Candida) conditions, unless targeted agents are co-prescribed and a clinician approves. Do not use in or near the eyes with skin formulations; ocular-specific fusidic acid products exist in certain countries but require separate instructions. Avoid application to deep wounds, puncture wounds, animal bites, or significant burns without professional evaluation, as systemic therapy, debridement, or different antibiotics may be necessary.
Most people tolerate Fucidin well. The most frequent side effects are mild and localized: transient stinging or burning upon application, mild redness, dryness, itching, or irritation. These typically improve as the skin heals. A small number of users may develop contact dermatitis (allergic or irritant), presenting as persistent redness, scaling, or worsening itch at the treated site; this warrants discontinuation and medical review. Folliculitis-like reactions can occur under occlusion or with heavy ointment layering. If a rash generalizes beyond the application area, or if there is facial swelling, wheezing, or difficulty breathing, seek urgent care for possible systemic allergy.
Systemic side effects are rare with topical use because absorption is minimal, but the risk increases with large surface area treatment, prolonged use, damaged skin barriers, or occlusive dressings. If unusual symptoms occur—muscle aches, dark urine, profound fatigue, or other systemic signs—stop use and contact a clinician. Secondary fungal overgrowth can occur with any topical antibiotic after prolonged courses; if new satellite pustules or beefy-red erythema arise, evaluation for yeast or fungal superinfection is appropriate. As with all antibiotics, prudent use is key: stop as advised and do not save leftovers for future, unadvised use.
Clinically significant drug interactions are unlikely with topical Fucidin because systemic absorption is low. The serious interaction profile widely discussed for oral or intravenous fusidic acid—particularly with statins leading to risk of myopathy or rhabdomyolysis—does not generally apply to limited topical use. Nonetheless, caution is prudent if very large areas are treated, if occlusive dressings are used, or if the skin barrier is severely compromised. To minimize local interactions, avoid simultaneous application of multiple topical products on the same site (antiseptics, benzoyl peroxide, retinoids, corticosteroids) unless instructed, as they may inactivate each other, alter pH, or increase irritation.
If you miss a dose of Fucidin, apply it as soon as you remember. If it is almost time for the next application, skip the missed dose and resume your regular schedule. Do not double apply to make up for a missed dose, as this increases irritation without improving effectiveness. Consistency helps maximize benefit, but short delays typically do not compromise outcomes when you complete the prescribed course.
Topical overdose is unlikely to cause severe problems, though excessive use may lead to marked skin irritation, redness, or contact dermatitis. If a large amount is inadvertently applied or covered under occlusion, gently wipe off the excess with a clean cloth and wash with mild soap and water. If Fucidin is accidentally swallowed, especially by a child, contact your local poison control center or seek medical attention, providing the product name, amount, and time of ingestion.
Store Fucidin at room temperature, typically 20–25°C (68–77°F), away from excess heat, moisture, and direct light. Do not freeze. Keep the tube tightly closed and out of reach of children. Do not use beyond the expiration date. Many topical antibiotics have a limited period for safe use after opening (for example, 3 months for some creams and longer for certain ointments), but specific guidance varies by manufacturer—check your package insert and label your tube with the first date of opening.
Pregnancy and breastfeeding: When used topically on limited areas, fusidic acid is generally considered low risk because systemic absorption is minimal. If breastfeeding, avoid applying to the nipple or areola; if treatment of the breast is necessary, cleanse thoroughly before nursing. As with all medications in pregnancy or lactation, discuss risks and benefits with a clinician before use. Pediatrics: Fucidin is frequently used in children for impetigo and minor infections; apply sparingly and avoid extensive areas or occlusion to limit systemic exposure. Geriatrics: Older adults may have thinner skin and higher sensitivity—use minimal effective amounts and monitor closely for irritation.
For superficial bacterial skin infections, alternatives include mupirocin (commonly first-line for impetigo in many guidelines), retapamulin (where available), and topical antiseptics in some mild cases. Mupirocin is widely used in the United States and has strong activity against S. aureus, including many MRSA strains, though resistance is a growing concern with indiscriminate use. Retapamulin is an option for impetigo in select age groups. When deeper tissue involvement is suspected (e.g., cellulitis, abscess), systemic antibiotics and procedures such as incision and drainage are more appropriate. Choice among Fucidin, mupirocin, or others depends on local resistance patterns, availability, patient tolerance, and clinician judgment.
Fusidic acid topical products (often branded as Fucidin in other countries) are not currently FDA-approved or widely marketed in the United States. U.S. clinicians usually treat comparable conditions with FDA-approved alternatives such as mupirocin or retapamulin. Importing prescription medicines for personal use is regulated and may not be lawful in many circumstances; always follow federal and state regulations and seek clinician guidance. If you need care for a suspected skin infection, a licensed healthcare professional can evaluate your case, confirm the diagnosis, and recommend safe, effective, and legally available treatment options in your state.
Physician House Calls of Kansas offers a legal and structured solution for people seeking access to Fucidin without a traditional paper prescription. Through clinician-led telehealth or in-person evaluation, they can determine whether fusidic acid is appropriate, discuss FDA-approved alternatives when indicated, and, where permitted by state law, coordinate compliant access—such as direct dispensing or pharmacy fulfillment—without requiring a separate formal prescription document in your hands. This preserves medical oversight, adheres to regulations, and helps patients receive timely treatment while maintaining safety, stewardship, and continuity of care.
Fucidin is a brand name for fusidic acid, a topical antibiotic used to treat mild-to-moderate bacterial skin infections, especially those caused by Staphylococcus aureus (staph), such as impetigo, infected eczema, and minor wound infections.
Fusidic acid blocks bacterial protein synthesis, stopping susceptible bacteria from growing and allowing your immune system to clear the infection. It’s bacteriostatic against most staph, with some bactericidal activity at high concentrations.
Common uses include impetigo, infected dermatitis/eczema, folliculitis, minor cuts and abrasions that have become infected, and boils (furuncles) after drainage. It is not effective for fungal, viral, or non-infectious skin conditions.
Fucidin (fusidic acid) is an antibiotic. Some products combine fusidic acid with a mild corticosteroid (for example, Fucidin H with hydrocortisone or Fucibet with betamethasone) to reduce inflammation when eczema is infected; those combos are different from plain Fucidin.
The cream is lighter, absorbs quickly, and suits moist or weeping areas. The ointment is greasier, forms an occlusive layer, and can be better for dry or crusted lesions. Both deliver fusidic acid effectively; choice depends on skin type and site.
Wash hands, gently clean and pat the area dry, then apply a thin film to the affected skin two to three times daily (or as prescribed). Use only on the area that needs treatment and wash hands after. Avoid getting it in the eyes, nose, or mouth unless instructed.
Typical courses last 5 to 7 days, sometimes up to 10 days. If there’s no improvement within 2–3 days, or if symptoms worsen (spreading redness, fever, increasing pain), seek medical advice. Don’t extend treatment unnecessarily to limit antibiotic resistance.
Fusidic acid is not a first-line acne treatment and should not be used routinely for acne because of resistance risk. It may be used briefly for clearly infected acne lesions if advised by a clinician, but dedicated acne therapies are preferred.
Yes. Fucidin is commonly used for localized non-bullous impetigo caused by staph or strep. In some regions, alternative topical antibiotics (like mupirocin or retapamulin) are preferred due to local resistance patterns—follow local guidance.
It can be used on minor, superficial infected wounds. Do not use it deep inside puncture wounds or on large open injuries without medical advice. After surgery, use only if a clinician confirms infection and recommends it.
Most people tolerate it well. Possible effects include mild stinging, itching, redness, or dryness at the application site. Rarely, allergic contact dermatitis or rash can occur; stop using and seek medical advice if severe irritation or signs of allergy develop.
Avoid if you have a known allergy to fusidic acid or any component of the product. In pregnancy and breastfeeding, short topical courses are generally considered low risk; avoid applying on the nipple just before feeds. For infants, use sparingly and avoid occlusion unless advised.
Topical use has minimal systemic absorption, so interactions are unlikely. However, oral/IV fusidic acid can interact with statins (risk of serious muscle injury); do not combine systemic fusidic acid with statins unless specifically directed and monitored by a clinician.
Yes. Overuse or prolonged courses can select for fusidic acid–resistant staph, including MRSA. Use the shortest effective course, avoid repeated unsupervised use, and don’t use for non-bacterial skin problems.
Avoid the eyes; if an eye infection is suspected, fusidic acid eye drops/gel (e.g., Fucithalmic) may be prescribed instead. Around the mouth and genitals, apply carefully and sparingly as directed, avoiding mucosal surfaces unless your clinician says otherwise.
Availability varies by country. In many regions, fusidic acid is prescription-only due to resistance concerns. Follow local regulations and medical advice.
Store at room temperature, tightly capped, away from heat and direct sunlight. Do not freeze. Follow the product’s expiry date; once opened, many creams/ointments remain usable until expiry if stored correctly—check the leaflet for any “after opening” guidance.
Apply when you remember, then continue your regular schedule. Don’t double-apply to “catch up.” Accidental overapplication is unlikely to cause harm but may increase irritation—wipe off excess and resume normal use.
A light, breathable dressing is fine if needed. Avoid airtight occlusive dressings unless instructed, as they can increase absorption and irritation and may promote resistance if used long term.
Fusidic acid is not known to cause photosensitivity, and alcohol has no notable interaction with topical use. Standard sun protection is still recommended for healing skin.
Both are topical antibiotics for skin infections and impetigo. Mupirocin often has stronger activity against MRSA and is preferred for nasal decolonization; fusidic acid is effective for many staph infections but resistance can be higher in some areas. Choice depends on local resistance and clinical judgment.
Both treat limited impetigo. Retapamulin is effective against common impetigo pathogens and may be used where fusidic acid resistance is problematic. Availability and cost differ by country; either may be appropriate based on local guidelines.
Ozenoxacin is a newer non-fluorinated quinolone topical antibiotic for impetigo with activity against some resistant strains and is used twice daily for 5 days. Fusidic acid is an older agent, usually used 2–3 times daily. Local availability, resistance data, and cost guide the choice.
Clindamycin gel is mainly for acne management (often combined with benzoyl peroxide), not general skin infections. Fucidin is for bacterial skin infections like impetigo or infected eczema. Use the drug best matched to the condition being treated.
Erythromycin gel targets acne and is less favored due to resistance. Fusidic acid targets staph-related skin infections. They serve different purposes; neither should be used long term to avoid resistance.
Gentamicin cream covers certain gram-negative bacteria and some staph, but local resistance patterns vary. Fusidic acid is particularly strong against staph. The better option depends on the suspected bacteria, site, and local resistance trends.
Triple antibiotic ointments are broad but carry higher risk of allergic contact dermatitis (especially neomycin). Fusidic acid is narrower, often better targeted for staph. For true infections, a prescription topical like fusidic acid or mupirocin is often preferred over OTC triple antibiotics.
Chloramphenicol is used topically in some regions and more commonly as an eye ointment for bacterial conjunctivitis. Fusidic acid is mainly for skin. For eye infections, chloramphenicol or fusidic acid eye preparations may be chosen based on local guidance and organism susceptibility.
Plain Fucidin treats infection alone. Combinations like Fucidin H (with hydrocortisone) or Fucibet (with betamethasone) reduce inflammation and itch in infected eczema but should be used short term and only when inflammation coexists with confirmed infection.
Topical Fucidin treats localized skin infections with minimal systemic exposure. Fusidic acid tablets are systemic antibiotics reserved for deeper or widespread staph infections (e.g., bone or joint), often in combination therapy and with careful monitoring for interactions and side effects.
No. Fucidin cream/ointment is for skin. Fucithalmic is a fusidic acid eye formulation for bacterial conjunctivitis and is designed for the eye’s pH and tissues. Do not use skin preparations in the eye.
Mupirocin ointment is the standard for intranasal MRSA decolonization in many protocols. Fusidic acid is generally not first choice for this purpose due to resistance considerations; follow your local decolonization guidelines.
Retinoids and benzoyl peroxide are core acne treatments that don’t drive antibiotic resistance. Fusidic acid is not recommended for routine acne management; reserve antibiotics for specific indications and short courses under medical advice.
Antiseptics like povidone-iodine can reduce bacterial load in minor cuts and grazes without selecting for specific antibiotic resistance, but they may be irritating and are not sufficient for established bacterial infections. Fucidin is better for confirmed localized bacterial skin infections.